The NRN1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Neuritin, neuritin 1, and NRN1. This antibody recognizes Human, Mouse, and Rat antigen. The NRN1 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants